diff --git a/renderdoc/driver/d3d11/d3d11_replay.cpp b/renderdoc/driver/d3d11/d3d11_replay.cpp
index 2c0cf57ba..d17769718 100644
--- a/renderdoc/driver/d3d11/d3d11_replay.cpp
+++ b/renderdoc/driver/d3d11/d3d11_replay.cpp
@@ -2891,6 +2891,9 @@ uint32_t D3D11Replay::PickVertex(uint32_t eventId, int32_t width, int32_t height
     if(cfg.ortho)
       guessProj = Matrix4f::Orthographic(cfg.position.nearPlane, cfg.position.farPlane);
 
+    if(cfg.position.flipY)
+      guessProj[5] *= -1.0f;
+
     pickMVPProj = projMat.Mul(camMat.Mul(guessProj.Inverse()));
   }
 
diff --git a/renderdoc/driver/d3d12/d3d12_replay.cpp b/renderdoc/driver/d3d12/d3d12_replay.cpp
index ba152a7c9..600be3fab 100644
--- a/renderdoc/driver/d3d12/d3d12_replay.cpp
+++ b/renderdoc/driver/d3d12/d3d12_replay.cpp
@@ -1762,6 +1762,9 @@ uint32_t D3D12Replay::PickVertex(uint32_t eventId, int32_t width, int32_t height
     if(cfg.ortho)
       guessProj = Matrix4f::Orthographic(cfg.position.nearPlane, cfg.position.farPlane);
 
+    if(cfg.position.flipY)
+      guessProj[5] *= -1.0f;
+
     pickMVPProj = projMat.Mul(camMat.Mul(guessProj.Inverse()));
   }
 
diff --git a/renderdoc/driver/gl/gl_debug.cpp b/renderdoc/driver/gl/gl_debug.cpp
index 845b309e1..739944dbc 100644
--- a/renderdoc/driver/gl/gl_debug.cpp
+++ b/renderdoc/driver/gl/gl_debug.cpp
@@ -2210,6 +2210,9 @@ uint32_t GLReplay::PickVertex(uint32_t eventId, int32_t width, int32_t height,
     if(cfg.ortho)
       guessProj = Matrix4f::Orthographic(cfg.position.nearPlane, cfg.position.farPlane);
 
+    if(cfg.position.flipY)
+      guessProj[5] *= -1.0f;
+
     pickMVPProj = projMat.Mul(camMat.Mul(guessProj.Inverse()));
   }
 
diff --git a/renderdoc/driver/vulkan/vk_debug.cpp b/renderdoc/driver/vulkan/vk_debug.cpp
index 2a709f6f0..1efe99388 100644
--- a/renderdoc/driver/vulkan/vk_debug.cpp
+++ b/renderdoc/driver/vulkan/vk_debug.cpp
@@ -1028,6 +1028,9 @@ uint32_t VulkanReplay::PickVertex(uint32_t eventId, int32_t w, int32_t h, const
     if(cfg.ortho)
       guessProj = Matrix4f::Orthographic(cfg.position.nearPlane, cfg.position.farPlane);
 
+    if(cfg.position.flipY)
+      guessProj[5] *= -1.0f;
+
     pickMVPProj = projMat.Mul(camMat.Mul(guessProj.Inverse()));
   }