diff --git a/renderdoc/driver/vulkan/vk_shader_cache.cpp b/renderdoc/driver/vulkan/vk_shader_cache.cpp
index 5b1bca32c..25824271c 100644
--- a/renderdoc/driver/vulkan/vk_shader_cache.cpp
+++ b/renderdoc/driver/vulkan/vk_shader_cache.cpp
@@ -521,6 +521,9 @@ void VulkanShaderCache::MakeGraphicsPipelineInfo(VkGraphicsPipelineCreateInfo &p
       0,                 // base pipeline index
   };
 
+  // never create derivatives
+  ret.flags &= ~VK_PIPELINE_CREATE_DERIVATIVE_BIT;
+
   pipeCreateInfo = ret;
 }
 
@@ -591,5 +594,8 @@ void VulkanShaderCache::MakeComputePipelineInfo(VkComputePipelineCreateInfo &pip
       0,                 // base pipeline index
   };
 
+  // never create derivatives
+  ret.flags &= ~VK_PIPELINE_CREATE_DERIVATIVE_BIT;
+
   pipeCreateInfo = ret;
 }