diff --git a/renderdoc/driver/shaders/dxil/dxil_disassemble.cpp b/renderdoc/driver/shaders/dxil/dxil_disassemble.cpp
index 51c4686ad..c0f100072 100644
--- a/renderdoc/driver/shaders/dxil/dxil_disassemble.cpp
+++ b/renderdoc/driver/shaders/dxil/dxil_disassemble.cpp
@@ -113,10 +113,10 @@ bool IsLLVMIntrinsicCall(const Instruction &inst)
 
 bool ShouldIgnoreSourceMapping(const Instruction &inst)
 {
-  // Do not set source mapping for handle creation instructions
   if(inst.op == Operation::Call)
   {
     rdcstr funcCallName = inst.getFuncCall()->name;
+    // Do not set source mapping for handle creation instructions
     if(funcCallName.beginsWith("dx.op."))
     {
       DXOp dxOpCode = DXOp::NumOpCodes;
@@ -131,6 +131,24 @@ bool ShouldIgnoreSourceMapping(const Instruction &inst)
         default: break;
       }
     }
+    else if(funcCallName.beginsWith("llvm."))
+    {
+      // Do not set source mapping for LLVM debug instructions
+      if(funcCallName.beginsWith("llvm.dbg."))
+      {
+        return true;
+      }
+      // Do not set source mapping for LLVM lifetime instructions
+      else if(funcCallName.beginsWith("llvm.lifetime."))
+      {
+        return true;
+      }
+      // Do not set source mapping for LLVM invariant instructions
+      else if(funcCallName.beginsWith("llvm.invariant"))
+      {
+        return true;
+      }
+    }
   }
   return false;
 }